Given that Pirfenidone is metabolised through the CYP1A2 enzyme pathway, any drug which inhibits this enzyme is probably going to precipitate the toxicity of pirfenidone: concomitant therapy would be to be prevented.lonapegsomatropin will decrease the level or influence of pirfenidone by influencing hepatic enzyme CYP1A2 metabolism.75 On top of tha
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